Glutamine promotes triglyceride absorption in a dose-dependent manner.

Umbelliprenin, a bioactive constituent from the genus Ferula has cytotoxic and apoptotic activity in a dose- and time-dependent manner

Glutamine promotes ovarian cancer cell proliferation through the mTOR/S6 pathway

Glutamine is one of the main nutrients used by tumor cells for biosynthesis. Therefore, targeted inhibition of glutamine metabolism may have anti-tumorigenic implications. In the present study, we aimed to evaluate the effects of glutamine on ovarian cancer cell growth. Three ovarian cancer cell lines, HEY, SKOV3, and IGROV-1, were assayed for glutamine dependence by analyzing cytotoxicity, cel...

Luminal leptin inhibits L-glutamine transport in rat small intestine: involvement of ASCT2 and BAT1

Ducroc R, Sakar Y, Fanjul C, Barber A, Bado A, Lostao MP. Luminal leptin inhibits L-glutamine transport in rat small intestine: involvement of ASCT2 and BAT1. Am J Physiol Gastrointest Liver Physiol 299: G179–G185, 2010. First published May 6, 2010; doi:10.1152/ajpgi.00048.2010.—L-glutamine is the primary metabolic fuel for enterocytes. Glutamine from the diet is transported into the absorptive...

Glutamine transporter in crypts compensates for loss of villus absorption in bovine cryptosporidiosis.

Cryptosporidium parvum infection represents a significant cause of diarrhea in humans and animals. We studied the effect of luminally applied glutamine and the PG synthesis inhibitor indomethacin on NaCl absorption from infected calf ileum in Ussing chambers. Infected ileum displayed a decrease in both mucosal surface area and NaCl absorption. Indomethacin and glutamine or its stable derivative...

Effect of dietary virgin olive oil on serum lipids levels in rats

Background: Relationship between olive oil consumption and low cardiovascular mortality and mobility is the aim of current study. We were investigated of dietary virgin olive oil (VOO) effects on serum lipids profile. Methods: Experimental mature male rats were treated with VOO for 30 days at 0.25, 0.5 and 0.75 ml/kg/day and control group treated with saline at the same time via gastric gava...